In the Spitzer Lab, we are passionate about developing better immune-based treatments for cancer and other diseases informed by fundamental scientific discovery.

Our Research

Our research focuses on the immune system, a decentralized assortment of cells that are distributed across the body to protect us from harm. We are fascinated by how these cells communicate with one another to decide when to initiate an immune response, how to carry it out, and when to shut it down and return to homeostasis. In order to understand these properties of the immune system, we use systems immunology techniques including single-cell analysis. Our work blends experimental and computational approaches to understand the complex circuits and regulatory processes that guide our immune systems to make decisions. A central emphasis for our work is understanding immune responses to cancer, both how they can work effectively and how they fail. We strive to fuel advances in therapies for patients with cancer and other diseases through basic discovery and a detailed understanding of the immune system.

Our Partners

Our People

The Spitzer Lab is a group of scientists passionate about improving lives through harnessing the immune system. We take pride in our constantly collaborative approach to science, in our inclusive lab culture, and in celebrating our diversity.

News

Media highlights of Spitzer Lab's research.
Successful Immunotherapy Requires System-Wide Immune Response
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Microbiome Research Program
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Tumours disrupt the immune scenery
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Tumors disrupt the immune system throughout the body
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Stay Updated

Keep up-to-date with the latest research from the Spitzer lab.

Incredibly excited and honored to have been selected for the @HHMINEWS #GilliamFellows award! A ...huge shoutout to my incredibly supportive PI Matt Spitzer, the @SpitzerLab, @j_eyquem , @Cil_MunSandoval , @ImmunoDiverse, Tammy Chang and the entire @UCSF community! 🎉 https://twitter.com/HHMINEWS/status/1552641027353313281

Thank you so much to @HHMINEWS #GilliamFellows for supporting the amazing @mayalopezich as a new ...Fellow! It is an honor to support her scientific journey as her adviser! https://www.hhmi.org/news/hhmi-awards-51-new-gilliam-fellowships-advance-diversity-and-inclusion-science

We are hiring a lab manager! Come join our collaborative and dynamic team and lead an exciting ...project in cancer immunotherapy! Here's the link: https://aprecruit.ucsf.edu/JPF03276 and please RT